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Primers 3 (1), 120
In contrast, there is some evidence of an enhancement of the maximum absorption via intrinsic factor, by up to a factor of 2, when the vitamin B12 is accompanied by food, but this is not consistently observed and probably only applies when the food quantity and vitamin B12 dose are sufficient to slow the passage of the vitamin B12 through the small intestine enough (about three hours or more) to allow each intrinsic factor receptor to absorb two molecules of vitamin B12 from the oral dose rather than one
The standard guideline is that an opened vial of BAC water should be discarded after 28 days
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A typical aggressive protocol might use 0.75mg daily for the first three days, 0.5mg for days four through seven, then 0.25mg to 0.5mg for the remainder of treatment
